Lutz Lab
Point-of-care diagnostics for
global health
Positions available with Lutz Labs
The Lutz group is recruiting postdoctoral researchers and research engineers to develop novel point-of-care diagnostics for global health and home testing. We have multiple projects in areas of HIV, respiratory infection (including Covid-19), and other infectious diseases. We are looking for strong thinkers who can contribute in the following areas:
- Point of care device engineering (mechanical prototyping, optical detection, low-cost electrical design)
- Development of novel assays (RNA/DNA detection, nucleic acid amplification)
Please send your CV to Dr. Lutz with the subject “Lutz Lab Hiring 2021”
Please send your CV to Dr. Lutz with the subject “Lutz Lab Hiring 2021”
Publications
Representative peer-reviewed journal publications
Harmony COVID-19: A ready-to-use kit, low-cost detector, and smartphone app for point-of-care SARS-CoV-2 RNA detection
Ultrasensitive hybridization capture: Reliable detection of <1 copy/mL short cell-free DNA from large-volume urine samples
Diagnosing pulmonary tuberculosis using sequence-specific purification of urine cell-free DNA
Near point-of-care, point-mutation test to detect drug resistance in HIV-1: a validation study in a Mexican cohort
The Seattle Flu Study: a multi-arm community-based prospective study protocol for assessing influenza prevalence, transmission, and genomic epidemiology
OLA-Simple: A software-guided HIV-1 drug resistance test for low-resource laboratories
Analytical Comparison of Methods for Extraction of Short Cell-Free DNA from Urine
1775. A Community-wide Study to Evaluate the Accuracy of Self-testing for Influenza: Works in Progress
Threshold-Based Quantification in a Multiline Lateral Flow Assay via Computationally Designed Capture Efficiency
Frequency characterization of flow magnitude and phase in resonant microfluidic circuits
Frequency tuning allows flow direction control in microfluidic networks with passive features
Flow control using audio tones in resonant microfluidic networks: towards cell-phone controlled lab-on-a-chip devices
Simplified paper format for detecting HIV drug resistance in clinical specimens by oligonucleotide ligation
Isothermal Strand Displacement Amplification (iSDA): A Rapid and Sensitive Method of Nucleic Acid Amplification for Point-of-Care Diagnosis
One-step purification and concentration of DNA in porous membranes for point-of-care applications
A versatile valving toolkit for automating fluidic operations in paper microfluidic devices
Swab Sample Transfer for Point-Of-Care Diagnostics: Characterization of Swab Types and Manual Agitation Methods
Long-term dry storage of an enzyme-based reagent system for ELISA in point-of-care devices
Dissolvable fluidic time delays for programming multi-step assays in instrument-free paper diagnostics
Subject of a “Viewpoints” article by George Whitesides, Lab on a Chip (2013), DOI: 10.1039/C3LC90066e. Also featured in Chemistry World, May 30, 2013, ”Microfluidic sugar paper” with quotes from George Whitesides
A Rapid, Multiplexed, High-Throughput Flow-Through Membrane Immunoassay: A Convenient Alternative to ELISA
New and Improved Ways to Treat Hydrocephalus: pursuit of a smart shunt
Progress toward multiplexed sample-to-result detection in low resource settings using microfluidic immunoassay cards
Two-dimensional paper networks: programmable fluidic disconnects for multi-step processes in shaped paper
Enhanced Sensitivity of Lateral Flow Tests Using a Two-Dimensional Paper Network Format
Transport in two-dimensional paper networks
Microfluidics without pumps: re-inventing the T-sensor & H-filter in paper networks
Chemical signal amplification in two-dimensional paper networks
Visualization and measurement of flow in two-dimensional paper networks
Controlled reagent transport in disposable 2D paper networks
Ultrasensitive hybridization capture: Reliable detection of <1 copy/mL short cell-free DNA from large-volume urine samples
Rapid protein depletion from complex samples using a bead-based microfluidic device for the point of care
People
Current lab members
Barry Lutz
Associate Professor
Ph.D. Chemical Engineering
Office: Foege N530N
Phone: (206) 685-9891
ResearchGate Profile
Garima Thakur
Lab Manager, Research Scientist
Ph.D. Chemistry
Office: Foege N209B
Phone: (206) 543-7331
ResearchGate Profile
Daniel Leon
Research Engineer
CrossLife TARA detection projects
TB-drug adherence at-home monitoring project
Enos Kline
Research Scientist
Protein engineering and assay design; HIV drug resistance, HIV self-test, Engineered polymerase, Harmony COVID-19 test
ResearchGate Profile
Jack Henry Kotnik
Research Scientist
Assay design, TARA Project; automated lateral flow strip interpretation; comparative accuracy of rapid diagnostic tests
Google Scholar
LinkedIn
ResearchGate Profile
Jordan Campbell
Research Scientist
OLA-Simple
Nuttada Panpradist, Ph.D.
BioE Research Assistant
Bob Atkinson
BioE Ph.D. Student
Point-of-care multiplexable nucleic acid assay for STDs
Shane Gilligan-Steinberg
BioE Ph.D. Student
