Welcome to Lutz Lab
Simple phenomena + clinical need + real-world constraints
As bioengineers we seek to apply scientific understanding to develop technology for improving human health. Our work is defined by manipulation of simple physical and biochemical phenomena to create devices for unmet clinical needs, and attention to real-world constraints improves the chances that our work will impact patients. The interplay between science, technology, clinical need, and real-world constraints creates a puzzle that requires a disciplined form of creativity and invention.
Representative peer-reviewed journal publications
Frequency characterization of flow magnitude and phase in resonant microfluidic circuits
Flow control using audio tones in resonant microfluidic networks: towards cell-phone controlled lab-on-a-chip devices
Simplified paper format for detecting HIV drug resistance in clinical specimens by oligonucleotide ligation
Isothermal Strand Displacement Amplification (iSDA): A Rapid and Sensitive Method of Nucleic Acid Amplification for Point-of-Care Diagnosis
A versatile valving toolkit for automating fluidic operations in paper microfluidic devices
Swab Sample Transfer for Point-Of-Care Diagnostics: Characterization of Swab Types and Manual Agitation Methods
Dissolvable fluidic time delays for programming multi-step assays in instrument-free paper diagnostics
Subject of a “Viewpoints” article by George Whitesides, Lab on a Chip (2013), DOI: 10.1039/C3LC90066e. Also featured in Chemistry World, May 30, 2013, ”Microfluidic sugar paper” with quotes from George Whitesides
A Rapid, Multiplexed, High-Throughput Flow-Through Membrane Immunoassay: A Convenient Alternative to ELISA
Progress toward multiplexed sample-to-result detection in low resource settings using microfluidic immunoassay cards
Enhanced Sensitivity of Lateral Flow Tests Using a Two-Dimensional Paper Network Format
Current lab members
Annie Wing-on-Wong, BioE Senior Capstone Student (OLA-Simple), Currently at Seattle Children's Hospital
Bella Spielman, BioE Senior Capstone Student (OLA-Simple), Currently at Accenture
Nikka Higga, BioE Senior Capstone Student (OLA-Simple), Currently at Seattle Children's Hospital
Doan Dinh, BioE Senior Capstone Student (Lab on a phone call project), Currently at Physio Control
Ian Andrews, BioE Senior Capstone Student (OLA-Simple), Currently at MIT
2015 and before
Shivani Dharmaraja, Masters Student (Point-of-Care Diagnostics for HIV)
Madhav Murthy, Undergraduate Researcher (Point-of-Care Diagnostics for HIV)
Ricky Liu, BioE Senior Capstone Student (Capillary-driven Point-of-Care Diagnostics, collaboration with Deok-Ho Kim)
Pranav Venkataraman, BioE Senior Capstone Student (Smart Shunt Project)
Marie Eberlein, BioE Senior Capstone Student (AC Fluidics Project)
Chenyi Wang, BioE Senior Capstone Student (Smart Shunt Project)
Bibianna Cha, Research Engineer (Smart Shunt Project)
Joel Relethford, Research Engineer (Smart Shunt Project)
James Wong. BioE Senior Capstone Student (AC Fluidics Project, Protein Printing)
Damon Cassisi. Research Engineer (Smart Shunt Project)
Rachana Shah. Graduate Student, MS 2010 (AC Fluidics Project)
Yoni Browning. Undergraduate Student (AC Fluidics Project)
Reid Philips. BioE Senior Capstone Student (AC Fluidics Project)
Updates from the inside and around the lab
Rahil passed his defense. Congratulations!
OLA Simple won the 2nd place $10k award at the annual Health Innovation Challenge
Dr. Lutz traveled to Nepal as part of a Bioengineering department group to make ties to Kathmandu University.
Rahil's paper on the flow magnitude and phase measurement in resonant devices is published and selected to be featured on the Front Cover of the Journal Analytical Methods.
08/22 - 09/15
Rahil got the Amazon Catalyst grant ($50k) and the GIX Innovation Award ($20k) to further work on commercializing his side projects.
Dr. Nathan White (UW, Emergency medicine) and Dr. Lutz submitted a new collaboration grant to work on a smartphone-powered thromboelastography device based on the resonant microfluidics project.
Nuttada received the prestigious 2017 UW Medicine Bud Tribble and Susan Barnes Graduate Discovery Fellowship. To learn more: https://bioe.uw.edu/nuttada-panpradist-receives-graduate-discovery-fellowship/
Rahil's paper featured on the Front Cover of the Journal Lab on a Chip Volume 17 Number 9
Nuttada passed her Generals! Congratulations!
Dr. Lutz traveled to Bangladesh to experience the global health needs first-hand.
Nuttada and her OLA-Simple team were featured on KIRO NEWS
Rahil passed his Generals. Congratulations!
Congratulation to Nuttada and Rahil for being selected as 10 finalists around the nation for the APF Student Technology Prize for Primary Healthcare. The competition, administered by Massachusetts General Hospital's Ambulatory Practice of the Future (APF) and sponsored by the Gelfand Family Charitable Trust, encourages and supports engineering students' efforts to develop innovative, clinically-relevant primary health care technology concepts.
Congratulations to Doan and Ian on graduating. Ian made it to coveted Husky 100 and is heading to MIT for graduate school. Doan will be working with Physio Control in Redmond WA. Good luck to you both.
Congratulations to Nuttada and Rahil to make it final round of APF Student Technology Prize. Both are independently getting $10k to further their research. Final proposals are due Aug 29.
Congratulations to Annie on receiving Mary Gates Research Scholarship!
Nuttada and Dr. James Lai (our collaborator on the OLA-Simple Project) wrote a chapter on point-of-care diagnostics as part of the book titled "Biomaterials Nanoarchitectonics" edited by Mitsuhiro Ebara. The book has just been published and now available at Elsevier website and can be downloaded via the UW library.
Bioengineer sophomore Jonathan Lim joined the Lutz Lab and will work on the TB project. Welcome Jonathan!!!
Nuttada's manuscript in PLoS ONE! "Simplified paper format for detecting HIV drug resistance in clinical specimens by oligonucleotide ligation" - see publications
02/20 - 02/21
Nuttada, Annie, Ian and Nikki are presenting at the XXV International HIV Drug Resistance Workshop in Boston, MA (a closed workshop, with a limited attendance of 200 delegates). Stop by and check out their poster presentations in the New Resistance Technologies and Interpretations Session!
Nuttada is co-lecturing with Dr. Sylvia LaCourse in the GH590 Global WACh BioEngineering Seminar on "Opportunities for Point-of-care TB Diagnostics" Come by at 4:30 - 5:30 PM at EEB 037 in the Electrical Engineering Building!
01/04 - 03/11
Dr. Lutz is teaching the Global Health Technology: Molecular Diagnostics!
01/04 - 03/11
Nuttada is TAing for BIOEN 531 Proposal Writing by Dr. Marta Scatena - one of the three Bioengineering Graduate Core classes! She is teaching a class on oral presentation and grant reviewing process on the Feb 8th, 2015.